The "P" in PICO represents the patient population or clinical problem
The population must be described in regards to their demographic, prognostic, and clinical characteristics. These characteristics are often presented in "Table 1" of a research article.
Population characteristics are also usually tested statistically when independent groups are being compared (between-subjects) or followed into the future (within-subjects).
If the "P" in PICO is primarily focused on a clinical problem, the focus is on the problem in terms of its biological, psychological, or physiological presentation within the context of clinical practice.
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