Equivalent Time Sample Design
Equivalent time sample designs use wash-out periods to establish longitudinal effects
The time period in between administration of the treatment and taking away the treatment is called a "washout" period. The effects of the treatment or non-treatment are allowed to dissipate before switching.
Equivalent time sample designs are powerful designs because each participant serves as their own control. Further, the stability of the treatment effect can be monitored across treatment administrations, washout periods, and non-treatment periods. Longitudinal effects can also be studied across the multiple observations.
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