Appraising systematic review evidence
Assess methodological rigor, publication bias, and pooled effects
Appraisal criteria for systematic review evidence
1. Did the systematic review contain only randomized trials?
2. Was a comprehensive and detailed literature search conducted for relevant trials?
3. Were the individual studies assessed for validity by independent raters?
4. Was individual or aggregate patient data used for the analysis?
5. Are the results consistent across studies?
6. Is the magnitude of the treatment effect clinically meaningful in the current clinical situation?
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